AR-C67085

• Description :

  AR-C67085 (PSB 0413; FPL 67085) is a potent platelet P2T receptor antagonist with an pIC50 value of 8.60. AR-C67085 inhibits ADP-induced platelet aggregation[1][2].

• CAS Number :

  [164992-25-0]

• Product Name Alternative :

  AR-C67085MX; PSB 0413; FPL 67085

• UNSPSC :

  12352005

• Target :

  P2Y Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/ar-c67085.html

• Smiles :

  NC1=C2N=CN([C@@H]3O[C@H](OP(OP(C(P(O)(O)=O)(Cl)Cl)(O)=O)(OC)=O)[C@@H](O)[C@H]3O)C2=NC(SCCC)=N1

• Molecular Formula :

  C14H22Cl2N5O12P3S

• Molecular Weight :

  648.24

• References & Citations :

  [1]Humphries RG, et al. A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis. Trends Pharmacol Sci. 1995 Jun;16 (6) :179-81.|[2]Ingall AH, et al. Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy. J Med Chem. 1999 Jan 28;42 (2) :213-20.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported