AR-C67085

• UNSPSC Description:

  AR-C67085 (PSB 0413; FPL 67085) is a potent platelet P2T receptor antagonist with an pIC50 value of 8.60. AR-C67085 inhibits ADP-induced platelet aggregation[1][2].

• Type:

  Reference compound

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ar-c67085.html

• Smiles:

  NC1=C2N=CN([C@@H]3O[C@H](OP(OP(C(P(O)(O)=O)(Cl)Cl)(O)=O)(OC)=O)[C@@H](O)[C@H]3O)C2=NC(SCCC)=N1

• Molecular Weight:

  648.24

• References & Citations:

  [1]Humphries RG, et al. A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis. Trends Pharmacol Sci. 1995 Jun;16(6):179-81.|[2]Ingall AH, et al. Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy. J Med Chem. 1999 Jan 28;42(2):213-20.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  164992-25-0