AR-C67085

CAT: 0804-HY-122048Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-122048Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AR-C67085 (PSB 0413; FPL 67085) is a potent platelet P2T receptor antagonist with an pIC50 value of 8.60. AR-C67085 inhibits ADP-induced platelet aggregation[1][2].
CAS Number
[164992-25-0]
Product Name Alternative
AR-C67085MX; PSB 0413; FPL 67085
UNSPSC
12352005
Target
P2Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ar-c67085.html
Smiles
NC1=C2N=CN([C@@H]3O[C@H](OP(OP(C(P(O)(O)=O)(Cl)Cl)(O)=O)(OC)=O)[C@@H](O)[C@H]3O)C2=NC(SCCC)=N1
Molecular Formula
C14H22Cl2N5O12P3S
Molecular Weight
648.24
References & Citations
[1]Humphries RG, et al. A novel series of P2T purinoceptor antagonists: definition of the role of ADP in arterial thrombosis. Trends Pharmacol Sci. 1995 Jun;16 (6) :179-81.|[2]Ingall AH, et al. Antagonists of the platelet P2T receptor: a novel approach to antithrombotic therapy. J Med Chem. 1999 Jan 28;42 (2) :213-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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