BMS-961955

• Description :

  BMS-961955 is an orally active inhibitor of HCV NS5B polymerase. BMS-961955 exhibits potent inhibitory activity against HCV genotype 1 (GT-1a/1b) replicons with EC50s of 4.3 nM and 7.9 nM, respectively. BMS-961955 can be used for the study of HCV infection[1].

• CAS Number :

  [1431328-92-5]

• UNSPSC :

  12352005

• Target :

  HCV

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  CN1CC(CC2)N(C([C@@]34CN5C(C(C=CC(F)=C6)=C6[C@]3([H])C4)=C(C7CCCCC7)C8=C5C=C(C(NS(=O)(C9(C)CC9)=O)=O)C=C8)=O)C2C1

• Molecular Formula :

  C37H43FN4O4S

• Molecular Weight :

  658.83

• References & Citations :

  [1]Zheng BZ, et al. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2017 Aug 1;27 (15) :3294-3300.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported