RP-60503

• Description :

  RP-60503 is an orally active anxiolytic cyclopyrrolone derivative with low sedative potential. RP-60503 binds to the gamma-aminobutyric acidA (GABA) /benzodiazepine receptor with a Ki value of 1.16 nM. RP-60503 can be used for the research of neurological disease[1].

• UNSPSC :

  12352005

• Target :

  GABA Receptor

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(OC1N(C2=NC3=NC(Cl)=CC=C3C=C2)C(C4=C1C=CC=C4)=O)CCCNC(C)=O

• Molecular Formula :

  C22H19ClN4O4

• Molecular Weight :

  438.86

• References & Citations :

  [1]Doble A, et al. RP 59037 and RP 60503: anxiolytic cyclopyrrolone derivatives with low sedative potential. interaction with the gamma-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent. J Pharmacol Exp Ther. 1993 Sep;266 (3) :1213-26.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [117705-18-7]