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RP-60503

CAT: 0804-HY-101643Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101643Size:1 Each
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Description
RP-60503 is an orally active anxiolytic cyclopyrrolone derivative with low sedative potential. RP-60503 binds to the gamma-aminobutyric acidA (GABA) /benzodiazepine receptor with a Ki value of 1.16 nM. RP-60503 can be used for the research of neurological disease[1].
CAS Number
117705-18-7
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(OC1N(C2=NC3=NC(Cl)=CC=C3C=C2)C(C4=C1C=CC=C4)=O)CCCNC(C)=O
Molecular Formula
C22H19ClN4O4
Molecular Weight
438.86
References & Citations
[1]Doble A, et al. RP 59037 and RP 60503: anxiolytic cyclopyrrolone derivatives with low sedative potential. interaction with the gamma-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent. J Pharmacol Exp Ther. 1993 Sep;266 (3) :1213-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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