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RP-69758

CAT: 0804-HY-116260Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116260Size:1 Each
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Description
RP-69758 is a potent and selective non-peptide cholecystokinin-B (CCKB) /gastrin receptor antagonist. RP-69758 exhibits >200-fold selectivity for CCKB over CCKA receptors. RP-69758 antagonizes CCK-8-induced neuronal firing in rat hippocampal slices. RP-69758 inhibits Pentagastrin -induced gastric acid secretion in the rat. RP-69758 can be used for neurological disorders and gastrointestinal disease research[1].
CAS Number
138562-23-9
UNSPSC
12352005
Target
Cholecystokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease; Inflammation/Immunology
Smiles
O=C(CC1=CC=CC(NC(NCC(N(C2=CC=CC=C2)CC(N(C3=CC=CC=C3)C)=O)=O)=O)=C1)O
Molecular Formula
C26H26N4O5
Molecular Weight
474.51
References & Citations
[1]Bertrand P, et al. Pharmacological properties of ureido-acetamides, new potent and selective non-peptide CCKB/gastrin receptor antagonists. Eur J Pharmacol. 1994 Sep 12;262 (3) :233-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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