ZG-2291

CAT: 0931-MF-0148438-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0148438-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2962103-40-6
Bioactivity
ZG-2291 is a selective inhibitor targeting FIH (hypoxia-inducible factor inhibitor) with oral activity. It selectively inhibits FIH by binding to it and inducing a conformational flip in a catalytically crucial tyrosine, without affecting other 2OG oxidases of the JmjC subfamily. ZG-2291 promotes thermogenesis and ameliorates obesity symptoms and metabolic dysfunctions in ob/ob mice. This compound holds promise for research in the field of obesity-related diseases.
Smiles
O=C(O)CNC(=O)C=1N=CC(=CC1O)C=2ON=C(C2)C=3C=CC=C(Cl)C3
Molecular Formula
C17H12ClN3O5
Molecular Weight
373.75
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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