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ZG-126

CAT: 0013-GTR19262854-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262854-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ZG-126 is an agonist of the vitamin D receptor (VDR) and an inhibitor of histone deacetylase (HDAC) with an IC50 range of 0.63-67.6 μM. It demonstrates cytotoxicity in cancer cell lines MDA-MB-231 and 4T1. In mouse models, ZG-126 exhibits antitumor and antimetastatic effects against melanoma and triple-negative breast cancer (TNBC) . Additionally, it shows anti-inflammatory activity by reducing macrophage infiltration and polarization to the immunosuppressive M2 subtype.
CAS Number
3049802-32-3
Field of Research
Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Smiles
O=C (NCCCCC (=O) NO) C1=CC=C (C=C1) C (C=2N=C (C (OCC (O) C (C) (C) C) =CC2) C) (CC) CC
Molecular Formula
C29H43N3O5
Molecular Weight
513.67
Storage Conditions
-20°C
Notes
For research use only.

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