ZG-2033

• Target:

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways:

  Chromatin/Epigenetic|||Metabolism

• Bioactivity:

  ZG-2033 (Compound 26) is an orally active HIF-2? agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.

• Smiles:

  N=1SC=2C=CC=CC2C1NC=3C=C(OC)C=C(OC)C3

• Molecular Formula:

  C15H14N2O2S

• Molecular Weight:

  286.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2685739-28-8