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22-SLF

CAT: 0931-T89030-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T89030-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, FKBP
Related Pathways
Immunology/Inflammation, Autophagy, Apoptosis, PROTAC
Bioactivity
22-SLF is a PROTAC degrader that operates by FBXO22-dependent degradation of FK506 Binding Protein 12 (FKBP12) with a DC50 of 0.5 μM. Additionally, 22-SLF can degrade other endogenous proteins, such as BRD4 and the EML4-ALK fusion protein (EML4-ALK fusion protein) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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