22-SLF

• Target:

  PROTACs|||FKBP

• Related Pathways:

  Immunology/Inflammation|||Autophagy|||Apoptosis|||PROTAC

• Bioactivity:

  22-SLF is a PROTAC degrader that operates by FBXO22-dependent degradation of FK506 Binding Protein 12 (FKBP12) with a DC50 of 0.5 µM. Additionally, 22-SLF can degrade other endogenous proteins, such as BRD4 and the EML4-ALK fusion protein (EML4-ALK fusion protein) .

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C