Products for Research Use Only
RegisterLogin

CDD-1653

CAT: 0931-T88619-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T88619-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
3034216-44-6
Target
TGF-beta/Smad
Related Pathways
Stem Cells
Bioactivity
CDD-1653 is a potent BMPR2 selective inhibitor with an IC50 of 2.8 nM. It acts by inhibiting the binding of ATP to the kinase domain of BMPR2, thereby affecting the phosphorylation of the transcription factors SMAD1/5/8, which play a crucial role in the BMP signaling pathway. CDD-1653 is utilized in research related to diseases associated with the BMP signaling pathway.
Smiles
O=C1N(C=2C=CC=CC2)CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)C1
Molecular Formula
C21H22N6O4S
Molecular Weight
454.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

CID 167312383
CAS Number3034216-44-6
PubChem CID167312383
IUPAC Name3-[[5-methoxy-4-(3-oxo-4-phenylpiperazin-1-yl)pyrimidin-2-yl]amino]benzenesulfonamide
Molecular FormulaC21H22N6O4S
Molecular Weight454.5
XLogP1.9
Topological Polar Surface Area139
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Heavy Atom Count32
Formal Charge0
Complexity741
SMILES
COC1=CN=C(N=C1N2CCN(C(=O)C2)C3=CC=CC=C3)NC4=CC(=CC=C4)S(=O)(=O)N
InChI
InChI=1S/C21H22N6O4S/c1-31-18-13-23-21(24-15-6-5-9-17(12-15)32(22,29)30)25-20(18)26-10-11-27(19(28)14-26)16-7-3-2-4-8-16/h2-9,12-13H,10-11,14H2,1H3,(H2,22,29,30)(H,23,24,25)
InChIKey
MHMPZSOMHQSWEN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of CID 167312383
CAS: 3034216-44-6
CID: 167312383
Formula: C21H22N6O4S
MW: 454.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight454.5
XLogP31.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass454.14232438
Monoisotopic Mass454.14232438
Topological Polar Surface Area139 Ų
Heavy Atom Count32
Formal Charge0
Complexity741
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T210217-01CDD-2807
T89314-01CDD-3290
T79346-01CDD-1845
T79345-01CDD-1733
T205131-01CDD-1281
T206617-01CDD-2789
T205172-01CDD-1115
T205082-01CDD-1431
T79344-01CDD-1819
T72058L-01CDD-1102 HCl

Alternative Products

CatalogName
GTR19236422-01CDD-1653
HY-162565-01CDD-2807
HY-177143CDD-1498
HY-171248CDD-1115
MBS5821008CDD-1845
GTR19249583-01CDD-1431
GTR17975534Cdd Antibody
HY-177141CDD-1154
HY-173149CDD-2789
HY-171247CDD-1281

Popular Products