CDD-1431

• Target :

  TGF-beta/Smad

• Related Pathways :

  Stem Cells

• Bioactivity :

  CDD-1431 is a highly selective BMPR2 kinase inhibitor with a Kiapp of 20.6 nM. It inhibits BRE reporter gene activity, exhibiting an IC50 of 4.87 ?M. BMPs regulate cellular processes across various tissue types such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.

• Smiles :

  O=C(NCC=1C=CC=C(C1)N2CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)CC2)C5=CC=C(C=C5)CCC(=O)NC

• Molecular Formula :

  C33H38N8O5S

• Molecular Weight :

  658.77

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3034216-31-1