TLR7 agonist 20

CAT: 0931-MF-0148048-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0148048-01Size:25 mg
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CAS Number
3029695-00-6
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 ?M for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.
Smiles
OCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC
Molecular Formula
C22H24N4O
Molecular Weight
360.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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