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TLR7 agonist 9

CAT: 0804-HY-152726Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152726Size:1 Each
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Description
TLR7 agonist 9 (compound 10) is an aonist of TLR7. TLR7 agonist 9 can be used for research of cancer and infectious disease[1]. TLR7 agonist 9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2389988-38-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-9.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(N2CC#CCO)=O)C3=C2C(NC(N)=N3)=O)O1
Molecular Formula
C14H17N5O7
Molecular Weight
367.31
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[2]Webber Stephen E, et al. TLR7 agonists for treatment of cancer and infectious disease. World Intellectual Property Organization, WO2019226977 A1. 2019-11-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7

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