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TLR7 agonist 14

CAT: 0931-T79749-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79749-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2832199-45-6
Target
Others, TLR
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Compound 17b, a TLR7 agonist also known as TLR7 agonist 14, exhibits high potency with an EC50 of 18 nM. It effectively activates mouse macrophages and human peripheral blood mononuclear cells (hPBMCs) at low-nanomolar concentrations [1].
Smiles
C(N1C=2C=3C(N=C(N)C2N=C1CCCC)=CC=CC3)C4=CC=C(NC(CCNC(OC(C)(C)C)=O)=O)C=C4
Molecular Formula
C29H36N6O3
Molecular Weight
516.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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