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TLR7 agonist 21

CAT: 0931-T210198-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T210198-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
TLR7 agonist21 (Compound 27B) is a selective activator of Toll-like receptor 7 (TLR7), with an EC50 of 17.53 nM for human TLR7 and 41.7 nM for mouse TLR7. It induces the secretion of pro-inflammatory cytokines, including IL-6, TNF-α, IFN-α1, and IL-4. Acting as a vaccine adjuvant, TLR7 agonist21 enhances IgG and IgA levels, offering protection for mice against influenza virus infection.
Molecular Formula
C22H33N7O
Shipping Conditions
Ice Packs
Storage Temperature
-20°C