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TLR7 agonist 18

CAT: 0931-T209088-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209088-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
TLR7 agonist18 (Compound 21a) is a selective Toll-like receptor 7 (TLR7) agonist with an EC50 of 7.8 μM. It demonstrates no cytotoxicity in an HEK293 cell line co-transfected with the hTLR7 gene and can induce the secretion of several cytokines, including IL-1β, IL-12p70, IL-8, and TNF-α. This compound is useful in research related to vaccines, asthma, allergies, and cancer treatment.
Molecular Formula
C18H16F4N4O
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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