CB07-Exatecan

• Target :

  Drug-Linker Conjugates for ADC|||Topoisomerase

• Related Pathways :

  Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Bioactivity :

  CB07-Exatecan, an ADC drug-linker conjugate, is utilized in the synthesis of ADCs and has demonstrated effectiveness in inhibiting the growth of HER2-positive cancer cells when conjugated with trastuzumab. This compound is valuable in cancer research [1].

• Smiles :

  N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC([C@@H](NC(CN2C(=O)C=CC2=O)=O)CCNC(CCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8

• Molecular Formula :

  C71H94FN11O22

• Molecular Weight :

  1472.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2879247-31-9