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GHK-Cu acetate

CAT: 0931-T85063-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T85063-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
300801-03-0
Target
Others
Related Pathways
Others
Bioactivity
GHK-Cu acetate, a complex of the tripeptide Gly-His-Lys and a copper (II) ion, exhibits wound healing and anti-inflammatory properties. It enhances fibroblast proliferation, collagen production, and the release of pro-matrix metalloproteinase-2 (MMP-2) and glycosaminoglycans (GAGs), while also increasing decorin expression in rat wound tissue. Furthermore, at a concentration of 10 μM, it reduces levels of reactive oxygen species (ROS), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in LPS-stimulated RAW 264.7 cells. Additionally, GHK-Cu at 10 μg/g mitigates LPS-induced reductions in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels, decreases the accumulation of cells and total protein in bronchoalveolar lavage fluid (BALF), and thus, attenuates acute lung injury in mice.
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C(C)(O)=O.C(N[C@@H](CCCCN)C([O-])=O)(=O)[C@H]1[N-]2[Cu+2]([N]=3C(C1)=CNC3)[NH2]CC2=O
Molecular Formula
C14H22CuN6O4?C2H4O2
Molecular Weight
462
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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