Antitumor agent-49

• Target:

  Others|||NO Synthase

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  Antitumor agent-49 (Compound 10), a harmine derivative-furoxan hybrid featuring nitric oxide (NO) donating properties, exhibits cytotoxic effects against HepG2 cells, achieving an IC50 value of 1.79 µM and inducing significant NO production in vitro [1].

• Smiles:

  [Br-].O=C (OCCCCOC1=NON (=O) =C1S (=O) (=O) C=2C=CC=CC2) COC=3C=CC=4C5=CC=[N+] (C (=C5N (C4C3) CCCC=6C=CC=CC6) C) CC=7C=CC=CC7

• Molecular Formula:

  C42H41BrN4O8S

• Molecular Weight:

  841.77

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2763914-21-0