LVGRQLEEFL (mouse)

• Target:

  Amino Acids and Derivatives

• Related Pathways:

  Metabolism

• Bioactivity:

  G* Peptide, also denoted as LVGRQLEEFL (mouse), represents the amino acid sequence 113 to 122 ([113,122] apoJ) found in apolipoprotein J. This compound displays both anti-inflammatory and anti-atherogenic characteristics. When incorporated into an apoJ mimetic, it results in the formation of the HM-10/10 peptide, which functions as a novel chimeric high-density lipoprotein. The HM-10/10 peptide has been shown to confer protection to the retinal pigment epithelium (RPE) and photoreceptors against oxidant-induced cell death [1] [2].

• Smiles:

  [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@H](CC(C)C)N)=O)C(C)C)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)CCC(O)=O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O

• Molecular Formula:

  C55H90N14O16

• Molecular Weight:

  1203.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  608513-82-2