Parstatin (mouse)

• Target :

  Protease-activated Receptor

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 ?M), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.

• Molecular Formula :

  C189H326N58O57S3

• Molecular Weight :

  4419.19

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1065756-01-5