[Pro3]-GIP (Mouse)

• Target :

  IGF-1R

• Related Pathways :

  Tyrosine Kinase/Adaptors

• Bioactivity :

  GIP receptor antagonist (IC50 = 2.6?M) . Inhibits GIP-stimulated insulin release from pancreatic ? cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intraperitoneal glucose tolerance, insulin sensitivity, and glucose response to feeding in ob/ob mice.

• Molecular Formula :

  C225H342N62O64S

• Molecular Weight :

  4971.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C