BigLEN (mouse)

• Target:

  GPCR

• Related Pathways:

  Endocrinology/Hormones|||GPCR/G Protein

• Bioactivity:

  GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.

• Smiles:

  C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC(=O)[C@H]3N(C([C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@@H](NC([C@H](CC(C)C)N)=O)CCC(O)=O)=O)CC(N)=O)=O)CCC4)CO)=O)CCC3)CCC(N)=O)=O)C)=O)CCC2)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)CCC1)N5[C@H](C(O)=O)CCC5

• Molecular Formula:

  C78H130N24O22

• Molecular Weight:

  1756.03

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  501036-69-7