LVGRQLEEFL (mouse)

CAT: 0804-HY-P5169Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P5169Size:1 Each
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Description
LVGRQLEEFL (mouse) can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ) }. LVGRQLEEFL (mouse) exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death[1][2].
CAS Number
[608513-82-2]
UNSPSC
12352209
Target
Amino Acid Derivatives; Apolipoprotein
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lvgrqleefl-mouse.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C55H90N14O16
Molecular Weight
1203.39
References & Citations
[1]Su F, et al. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. Int J Mol Sci. 2019 Sep 27;20 (19) :4807. |[2]Mishra VK, et al. Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G (*) apolipoprotein J peptide using solution NMR. Biochim Biophys Acta. 2011 Jan;1808 (1) :498-507.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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