Cbl-b-IN-11

• Target :

  E1/E2/E3 Enzyme

• Related Pathways :

  Ubiquitination

• Bioactivity :

  Cbl-b-IN-11 (Compound 466) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.4 nM and 6.1 nM, respectively [1].

• Smiles :

  C(C1(CC(F)(F)C1)C2=CC(=CC(NCC)=C2)N3CC=4C(C3=O)=CC(CNC5(C)CCC5)=CC4C(F)(F)F)C=6N(C)C=NN6

• Molecular Formula :

  C31H35F5N6O

• Molecular Weight :

  602.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2815225-15-9