Cbl-b-IN-11

Cbl-b-IN-11

• CAS Number: 2815225-15-9
• UNSPSC Description: Cbl-b-IN-11 (Compound 466) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.4 nM and 6.1 nM, respectively[1].
• Target Antigen: E1/E2/E3 Enzyme
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cbl-b-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(CN1C3=CC(NCC)=CC(C4(CC(F)(C4)F)CC5=NN=CN5C)=C3)C(C(F)(F)F)=CC(CNC6(CCC6)C)=C2
• Molecular Weight: 602.64
• References & Citations: [1]Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported