Products for Research Use Only

DGKα-IN-8

CAT: 0931-T79828-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79828-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2886717-70-8
Target
Others, HIV Protease
Related Pathways
Others, Proteases/Proteasome, Microbiology/Virology
Bioactivity
DGKα-IN-8 (Example 51), a potent diacylglycerol kinase alpha (DGKα) inhibitor, exhibits an IC50 of 22.491 nM and an EC50 of 0.256 nM. It is applicable in cancer research, particularly for solid tumors, and in studies of viral infections such as HIV and hepatitis B virus [1].
Smiles
N(CC(F)F)(C=1C=2C(C3=C(N1)N=NN3C)=CC(Cl)=CC2)C4=CC(C#CC(C)(C)O)=CC(F)=C4
Molecular Formula
C23H19ClF3N5O
Molecular Weight
473.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C