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DGKζ-IN-4

CAT: 0804-HY-156574-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156574-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DGKζ-IN-4 is a DGK-zeta inhibitor. DGKζ-IN-4 can be used as an active component of pharmaceutical compositions. DGKζ-IN-4 is used to treat cancers associated with immune cell activation or cancers resistant to anti-PD-1 antibody/anti-PD-11 antibody treatment[1].
CAS Number
2778366-77-9
UNSPSC
12352005
Target
DGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dgkζ-in-4.html
Purity
99.52
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=C(N2C[C@H](N(CC2)C(OC(C)(C)C)=O)CO)C([N+]([O-])=O)=CC=C1OC3=C(C=CC=C3)Cl)F
Molecular Formula
C23H25ClF3N3O6
Molecular Weight
531.91
References & Citations
[1]Tu-Sekine B, et al. DGK-θ: Structure, Enzymology, and Physiological Roles. Front Cell Dev Biol. 2016 Sep 14;4:101.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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