DGK?-IN-2

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  DGK?-IN-2 (example 48), a potent DGK? inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.

• Smiles:

  C (N) (=O) C1=C (C=2C (N (C) C1=O) =CC=CC2) N3CCC (OC4=CC=C (OC (F) (F) F) C=C4) CC3

• Molecular Formula:

  C23H22F3N3O4

• Molecular Weight:

  461.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2648556-92-5