Products for Research Use Only

DGKα-IN-2

CAT: 0931-T79821-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79821-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2648556-92-5
Target
Others
Related Pathways
Others
Bioactivity
DGKα-IN-2 (example 48), a potent DGKα inhibitor with an IC50 of 0.9 nM, significantly enhances the anti-tumor efficacy of anti-PD-1 therapy by amplifying T cell proliferation and function, making it a valuable agent for cancer and immunological research.
Smiles
C(N)(=O)C1=C(C=2C(N(C)C1=O)=CC=CC2)N3CCC(OC4=CC=C(OC(F)(F)F)C=C4)CC3
Molecular Formula
C23H22F3N3O4
Molecular Weight
461.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C