DGK-IN-9

• Target:

  Interleukin|||Others

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  DGK-IN-9 (Compound 15) is an orally active and selective inhibitor of DGK? with an IC50 of 6.1 nM. It is capable of activating IL-2 expression in Jurkat-IL2 nanoluc cells with an EC50 of 153 nM. DGK-IN-9 is applicable in tumor research.

• Smiles:

  O=C(NC1=CC=C(OC=2C=CC=CC2F)C(=C1N(C)CCNC)C(F)(F)F)C3=NC(=CS3)C=4C=NN=CC4

• Molecular Formula:

  C25H22F4N6O2S

• Molecular Weight:

  546.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3081525-23-4