Products for Research Use Only
RegisterLogin

DGKα/ζ-IN-1

CAT: 0804-HY-156573Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-156573Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DGKα/ζ-IN-1 (Compound II) is a DGK target inhibitor. DGKα/ζ-IN-1 can enhance the function of T cells, and has a synergistic effect with PD-1, which has therapeutic effects IN both immune and tumor[1].
CAS Number
2830643-06-4
UNSPSC
12352005
Target
DGK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dgkα-ζ-in-1.html
Solubility
10 mM in DMSO
Smiles
CC[C@H](CN(C(C1=NC(C#N)=CC=C1N2C)=NC2=O)[C@H](C3)CC)N3C(C4=CC=C(C=C4)F)C5=NC(C6CC6)=NO5
Molecular Formula
C29H31FN8O2
Molecular Weight
542.61
References & Citations
[1]Tu-Sekine B, et al. DGK-θ: Structure, Enzymology, and Physiological Roles. Front Cell Dev Biol. 2016 Sep 14;4:101.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-156574-01DGKζ-IN-4
HY-156570DGKα-IN-3
HY-178327DGKα&ζ-IN-2
HY-156578DGKα-IN-8
HY-169317DGKζ-IN-6
HY-177601DGK-IN-11
HY-164905DGK-IN-8
HY-156576DGKα-IN-6
HY-156571DGKα-IN-4
HY-156572DGKζ-IN-3

Alternative Products

CatalogName
BA7292-1DGK-IN-1
GTR19218754-01DGKζ-IN-1
T79824-01DGKα&ζ-IN-1
T204664-01DGKζ-IN-9
T204301-01DGKα-IN-9
313409-01DGK-beta
342940-01DGK-κ discontinued
342938-01DGK-θ discontinued
342933-01DGK-β discontinued
T79821-01DGKα-IN-2

Popular Products