Products for Research Use Only

ZMF-23

CAT: 0931-T79369-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79369-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PAK, HDAC
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Cytoskeletal Signaling
Bioactivity
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-α-regulated necroptosis and augmenting apoptosis. The compound effectively hampers the Warburg effect and cell motility, positioning it as a potential research tool for triple-negative breast cancer (TNBC) [1].
Molecular Formula
C22H23Cl2N5O3
Molecular Weight
476.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C