ZMF-23

• Target:

  PAK|||HDAC

• Related Pathways:

  Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Cytoskeletal Signaling

• Bioactivity:

  ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-?-regulated necroptosis and augmenting apoptosis. The compound effectively hampers the Warburg effect and cell motility, positioning it as a potential research tool for triple-negative breast cancer (TNBC) [1].

• Molecular Formula:

  C22H23Cl2N5O3

• Molecular Weight:

  476.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C