ZMF-24

• Target :

  Apoptosis|||PERK

• Related Pathways :

  Apoptosis

• Bioactivity :

  ZMF-24 is an anti-triple-negative breast cancer (TNBC) agent that exhibits IC50 values of 0.22 ?M and 0.44 ?M against BT-549 and MDA-MB-231 TNBC cell proliferation, respectively. It targets the eukaryotic translation initiation factor 3 subunit D (EIF3D), disrupting TNBC's energy supply by inhibiting glycolysis. Additionally, ZMF-24 induces TNBC cell apoptosis (apoptosis) by stimulating sustained endoplasmic reticulum stress.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C