CSF1R-IN-23

• Target:

  C-Fms

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Bioactivity:

  CSF1R-IN-23 (Compound 7dri), a selective colony-stimulating factor-1 receptor (CSF1R) inhibitor, exhibits an IC50 of 36.1 nM. This compound acts as an antineuroinflammatory agent in a mouse model and is noted for its blood-brain barrier (BBB) permeability [1].

• Smiles:

  N(C(=O)C1=NOC(C)=C1)C2=C(C=C(C=C2)C3CC(C)(C)NC(C)(C)C3)C=4CCC(C)CC4

• Molecular Formula:

  C27H37N3O2

• Molecular Weight:

  435.6

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2935480-17-2