AZ-23

• Target:

  Trk receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Purity:

  0.994

• Bioactivity:

  AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.

• Smiles:

  CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1

• Molecular Formula:

  C17H19ClFN7O

• Molecular Weight:

  391.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  915720-21-7