ZMF-10

CAT: 0931-T63063-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T63063-01Size:25 mg
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CAS Number
2415295-37-1
Target
Apoptosis|||Others|||PAK
Related Pathways
Apoptosis|||Others|||Cytoskeletal Signaling
Bioactivity
ZMF-10 is a potent inhibitor of PAK1, and can act on PAK1 (IC50:174 nM), PAK2 (IC50:1.038 ?M) and PAK3 (IC50:1.372 ?M) . ZMF-10 inhibited PAK1 activity and affected Pak1-regulated apoptosis, endoplasmic reticulum stress and migration in MDA-MB-231 cells. ZMF-10 can be used to study cancer.
Smiles
N(C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)=O)C2CCN(C3=C4C(NN=C4)=NC=N3)CC2
Molecular Formula
C19H17F6N7O
Molecular Weight
473.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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