ZMF-10

• Target :

  Apoptosis|||Others|||PAK

• Related Pathways :

  Apoptosis|||Others|||Cytoskeletal Signaling

• Bioactivity :

  ZMF-10 is a potent inhibitor of PAK1, and can act on PAK1 (IC50:174 nM), PAK2 (IC50:1.038 ?M) and PAK3 (IC50:1.372 ?M) . ZMF-10 inhibited PAK1 activity and affected Pak1-regulated apoptosis, endoplasmic reticulum stress and migration in MDA-MB-231 cells. ZMF-10 can be used to study cancer.

• Smiles :

  N(C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)=O)C2CCN(C3=C4C(NN=C4)=NC=N3)CC2

• Molecular Formula :

  C19H17F6N7O

• Molecular Weight :

  473.38

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2415295-37-1