RIPK2-IN-6

CAT: 0931-MF-0111008-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0111008-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2242432-02-4
Target
NF-?B|||p38 MAPK|||RIP kinase
Related Pathways
NF-?B|||MAPK|||Apoptosis
Bioactivity
RIPK2-IN-6 (Compound 15a) is an inhibitor of RIPK that specifically targets the phosphorylation of RIPK2, thereby suppressing the NF-?B and MAPK signaling pathways. It has demonstrated anti-inflammatory and anti-fibrotic activities in a mouse model of colitis induced by Dextran sodium sulfate.
Smiles
O=C1C2=C(OC=C2C)C3=CC=C4C=5C3=C1N(C5C(=O)CC4(C)C)CC=6C=CC=CC6
Molecular Formula
C26H21NO3
Molecular Weight
395.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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