RIPK2-IN-6

• Target:

  NF-?B|||p38 MAPK|||RIP kinase

• Related Pathways:

  NF-?B|||MAPK|||Apoptosis

• Bioactivity:

  RIPK2-IN-6 (Compound 15a) is an inhibitor of RIPK that specifically targets the phosphorylation of RIPK2, thereby suppressing the NF-?B and MAPK signaling pathways. It has demonstrated anti-inflammatory and anti-fibrotic activities in a mouse model of colitis induced by Dextran sodium sulfate.

• Smiles:

  O=C1C2=C(OC=C2C)C3=CC=C4C=5C3=C1N(C5C(=O)CC4(C)C)CC=6C=CC=CC6

• Molecular Formula:

  C26H21NO3

• Molecular Weight:

  395.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2242432-02-4