RIPK2-IN-2

CAT: 0931-T74572-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T74572-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2143956-20-9
Target
Others|||PROTACs|||RIP kinase
Related Pathways
Others|||NF-?B|||PROTAC|||Apoptosis
Bioactivity
RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor that effectively blocks RIP2-dependent pro-inflammatory signaling and regulates RIP2 kinase activity in autoinflammatory diseases [1].
Smiles
CN[C@@H](C)C(=O)N[C@@H](C1CCN(CC1)C(=O)c1cnc(nc1)N1CCN(CCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1ccc(F)cc1
Molecular Formula
C53H65FN14O7S2
Molecular Weight
1093.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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