RIPK2-IN-2

• Target :

  Others|||PROTACs|||RIP kinase

• Related Pathways :

  Others|||NF-?B|||PROTAC|||Apoptosis

• Bioactivity :

  RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor that effectively blocks RIP2-dependent pro-inflammatory signaling and regulates RIP2 kinase activity in autoinflammatory diseases [1].

• Smiles :

  CN[C@@H](C)C(=O)N[C@@H](C1CCN(CC1)C(=O)c1cnc(nc1)N1CCN(CCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(=O)N1CCC[C@H]1c1nc(cs1)C(=O)c1ccc(F)cc1

• Molecular Formula :

  C53H65FN14O7S2

• Molecular Weight :

  1093.3

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2143956-20-9