Products for Research Use Only

EGFR-IN-79

CAT: 0931-T79293-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79293-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
EGFR-IN-79 (compound 21), an EGFR inhibitor, exhibits antitumor activity through ROS-independent apoptosis and EGFR/AKT/mTOR-mediated autophagy. It effectively induces cell death in proliferating and quiescent zones of EJ28 spheroids and demonstrates a safety profile in zebrafish-based models [1].
Molecular Formula
C23H16ClN3O3
Molecular Weight
417.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C