HQL-79

• Target:

  Others|||PGE Synthase

• Related Pathways:

  Others|||Immunology/Inflammation

• Bioactivity:

  HQL-79 is a selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor. It inhibits the synthesis of PGD2 and acts as an anti-allergic agent (Kd: 0.8 ?M and IC50: 6 ?M) . It also shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.

• Smiles:

  C (CN1CCC (CC1) OC (c1ccccc1) c1ccccc1) Cc1nnn[nH]1

• Molecular Formula:

  C22H27N5O

• Molecular Weight:

  377.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  162641-16-9