HDAC-IN-59

• Target:

  Apoptosis|||HDAC

• Related Pathways:

  Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair

• Bioactivity:

  HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers the mitochondrial apoptotic pathway, leading to cell apoptosis [1].

• Smiles:

  O(C)C1=C(OC)C=C(CCC2=CC(OCC(NO)=O)=C(OC)C=C2)C=C1OC

• Molecular Formula:

  C20H25NO7

• Molecular Weight:

  391.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2944459-43-0