HDAC-IN-59

• Target :

  Apoptosis|||HDAC

• Related Pathways :

  Chromatin/Epigenetic|||Apoptosis|||DNA Damage/DNA Repair

• Bioactivity :

  HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers the mitochondrial apoptotic pathway, leading to cell apoptosis [1].

• Smiles :

  O(C)C1=C(OC)C=C(CCC2=CC(OCC(NO)=O)=C(OC)C=C2)C=C1OC

• Molecular Formula :

  C20H25NO7

• Molecular Weight :

  391.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2944459-43-0