HDAC-IN-57

• Target:

  Apoptosis|||HDAC

• Related Pathways:

  Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Apoptosis

• Purity:

  0.9862

• Bioactivity:

  HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with an IC50 value of 1.34 ??. HDAC-IN-57 has anti-tumor activity and can induce apoptosis.

• Smiles:

  C (NCC1=CC=C (C (NO) =O) C=C1) (=O) C=2C=C (N=CC2) C3=CC=C (OC) C=C3

• Molecular Formula:

  C21H19N3O4

• Molecular Weight:

  377.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2716217-79-5