STING agonist-26

CAT: 0931-T75094Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T75094Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2868261-48-5

Target

Others, STING

Related Pathways

Others, Immunology/Inflammation

Bioactivity

STING agonist-23 (CF508), a non-nucleotide small-molecule STING agonist, activates STING, thereby enhancing the phosphorylation of STING, TBK1, and IRF3. This activation elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. Moreover, STING agonist-23 demonstrates efficacy against SARS-CoV series strains [1].

Smiles

C(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCN7CCNCC7

Molecular Formula

C40H49N15O5

Molecular Weight

819.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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