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PROTAC BRD4 Degrader-7

CAT: 0931-T74090-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74090-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2413382-30-4
Target
Others, Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
PROTAC BRD4 Degrader-7, a potent bromodomain BRD4 inhibitor exemplified by compound 1a, demonstrates half-maximal inhibitory concentrations (IC50s) of 15.5 nM and 12.3 nM for BRD4-BD1 and BRD4-BD2, respectively [1].
Smiles
Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OC(C)(C)C)c1nnc(C)n-21)c1ccc(cc1)C#CCN
Molecular Formula
C26H29N5O2S
Molecular Weight
475.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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