Products for Research Use Only
RegisterLogin

PROTAC BRD2/BRD4 degrader-1

CAT: 0931-T18598-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T18598-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, Epigenetic Reader Domain, Others
Related Pathways
PROTAC, Chromatin/Epigenetic, Others
Bioactivity
PROTAC BRD2/BRD4 degrader-1 (compound 15) is a potent, selective degrader of BET proteins BRD4 and BRD2, achieving rapid, reversible, and unexpectedly selective elimination compared to BRD3. It effectively suppresses solid tumors with minimal cytotoxic effects and comprises a BET inhibitor, a connecting linker, and thalidomide as the ligand for cereblon (CRBN) /cullin 4A[1].
Smiles
O=C(NCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCC4=CC5=C(NS(=O)(C6=CC=CC=C6OC)=O)C=CC(N(C)C7=O)=C5C7=C4
Molecular Formula
C39H38N6O9S
Molecular Weight
766.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T13833-01PROTAC BRD4 Degrader-1
T78956-01PROTAC BRD3/BRD4-L degrader-2
T200664-01PROTAC BRD4-DCAF1 degrader-1
T18603-01PROTAC BRD4 degrader for PAC-1
T211940-01PROTAC BRD4 Degrader-37
T211537-01PROTAC BRD4 Degrader-38
T211533-01PROTAC BRD4 Degrader-36
T210772-01PROTAC BRD4 Degrader-35
T204774-01PROTAC BRD4 Degrader-29
T87259-01PROTAC BRD4 Degrader-20

Alternative Products

CatalogName
HY-130612PROTAC BRD2/BRD4 degrader-1
MBS5768134PROTAC BRD4 Degrader-1
GTR19275112-01PROTAC BRD2 BD1 Degrader-1
GTR19238700-01PROTAC BRD4-DCAF1 degrader-1
MBS5771462PROTAC BRD4 degrader for PAC-1
HY-175240PROTAC BRD4 Degrader-38
HY-174811PROTAC BRD4 Degrader-33
HY-162875PROTAC BRD4 Degrader-27
HY-135558PROTAC BRD4 Degrader-3
HY-143327PROTAC BRD4 Degrader-16

Popular Products