PROTAC BRD4 Degrader-3

• UNSPSC Description:

  PROTAC BRD4 Degrader-3 (compound 1004.1) is an efficacious PROTAC connected by ligands for von Hippel-Lindau and BRD4[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-degrader-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C(CN(C(N=CC(F)=C3)=C3F)C4=C5)=CN2)C(C4=CC(C[S](C)(=O)=O)=C5C(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N(C[C@@H]6O)[C@@H](C6)C(NOC7=CC=C(C(SC=N8)=C8C)C=C7)=O)=O)=O)=O)=CN1C

• Molecular Weight:

  1098.29

• References & Citations:

  [1]Peter Dragovich, et al. (4-hydroxypyrrolidin-2-yl)-hydroxamate compounds and methods of use thereof. WO2019084030A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2313234-00-1