PROTAC BRD4 Degrader-3

PROTAC BRD4 Degrader-3

• CAS Number: 2313234-00-1
• UNSPSC Description: PROTAC BRD4 Degrader-3 (compound 1004.1) is an efficacious PROTAC connected by ligands for von Hippel-Lindau and BRD4[1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-brd4-degrader-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C2=C(C(CN(C(N=CC(F)=C3)=C3F)C4=C5)=CN2)C(C4=CC(C[S](C)(=O)=O)=C5C(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N(C[C@@H]6O)[C@@H](C6)C(NOC7=CC=C(C(SC=N8)=C8C)C=C7)=O)=O)=O)=O)=CN1C
• Molecular Weight: 1098.29
• References & Citations: [1]Peter Dragovich, et al. (4-hydroxypyrrolidin-2-yl)-hydroxamate compounds and methods of use thereof. WO2019084030A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported