PROTAC BRD4 Degrader-23

PROTAC BRD4 Degrader-23

• UNSPSC Description: PROTAC BRD4 Degrader-23 (compound 17) is an effective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 can inhibit tumor cell proliferation under 405 nm light irradiation[1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-brd4-degrader-23.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)CN1[C@H](C(N(CC2=CC=C(C3=C(C)N=CS3)C=C2)CC4=CC(C(C=CC=C5)=C5O6)=C6C=C4[N+]([O-])=O)=O)C[C@@H](O)C1)=O)C[C@@H]7N=C(C8=CC=C(Cl)C=C8)C(C(C)=C(C)S9)=C9N%10C7=NN=C%10C
• Molecular Weight: 1213.86
• References & Citations: [1]Weng, Weizhi et al. Development of visible-light-activatable photocaged PROTACs. European journal of medicinal chemistry, vol. 265 116062. 16 Dec. 2023
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported