PROTAC BRD4 Degrader-23

• UNSPSC Description:

  PROTAC BRD4 Degrader-23 (compound 17) is an effective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 can inhibit tumor cell proliferation under 405 nm light irradiation[1].

• Target Antigen:

  PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-degrader-23.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)CN1[C@H](C(N(CC2=CC=C(C3=C(C)N=CS3)C=C2)CC4=CC(C(C=CC=C5)=C5O6)=C6C=C4[N+]([O-])=O)=O)C[C@@H](O)C1)=O)C[C@@H]7N=C(C8=CC=C(Cl)C=C8)C(C(C)=C(C)S9)=C9N%10C7=NN=C%10C

• Molecular Weight:

  1213.86

• References & Citations:

  [1]Weng, Weizhi et al. Development of visible-light-activatable photocaged PROTACs. European journal of medicinal chemistry, vol. 265 116062. 16 Dec. 2023

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported