LLY-507

CAT: 0804-HY-19313-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19313-01Size:5 mg
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Description
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 [1].
CAS Number
[1793053-37-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/LLY-507.html
Purity
98.47
Solubility
DMSO : 15 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CC(C2=CC=CC=C2N3CCN(CCN4C=C(C)C5=C4C=CC=C5)CC3)=CC(C#N)=C1)NCCCN6CCCC6
Molecular Formula
C36H42N6O
Molecular Weight
574.76
Precautions
H315, H319, H320
References & Citations
[1]Nguyen H, et al. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2. J Biol Chem. 2015 May 29;290 (22) :13641-13653.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SMYD2

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Alternative Products

CatalogName
MBS3602702-01LLY-507
A15813-25LLY-507 25mg
A15813-50LLY-507 50mg
A15813-100LLY-507 100mg
A15813-10LLY-507 10mg
A15813-1LLY-507 1mg
A15813-2LLY-507 2mg
A15813-5LLY-507 5mg
A15813-10mM-DLLY-507 10mM * 1mL in DMSO
bs-60259C-01LLY-507 --- Protein-lysine Methyltransferase SMYD2 Inhibitor

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