HDAC-IN-49

• Target:

  Others|||HDAC

• Related Pathways:

  DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Others

• Bioactivity:

  HDAC-IN-49 is a potent, non-selective inhibitor of HDAC (HDAC), demonstrating IC50 values of 13 nM for HDAC1, 14 nM for HDAC2, 21 nM for HDAC3, 1880 nM for HDAC4, and 10 nM for HDAC6. This compound exhibits significant antileukemic activity while maintaining low cytotoxicity towards healthy cells.

• Smiles:

  CN (C) C1=CC=C (C=C1) C (=O) N (CC2=C (C=C (C=C2) C (=O) NO) F) CC (=O) NCC3=CC=CC=C3

• Molecular Formula:

  C26H27FN4O4

• Molecular Weight:

  478.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C