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HDAC6-IN-49

CAT: 0931-T200554-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200554-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
HDAC, Cholinesterase (ChE), Histamine Receptor, 5-HT Receptor, Monoamine Oxidase
Related Pathways
Neuroscience, DNA Damage/DNA Repair, Immunology/Inflammation, GPCR/G Protein, Chromatin/Epigenetic
Bioactivity
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 μM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R) . HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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