Products for Research Use Only

TK-684

CAT: 0931-T211274-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211274-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, Phosphatase
Related Pathways
Apoptosis, Metabolism
Bioactivity
TK-684 is a potent and selective allosteric inhibitor of SHP2, with IC50 values of 2.1 nM for SHP2WT and greater than 1000 nM for SHP2PTP. It inhibits cell proliferation and induces apoptosis (apoptosis) . Additionally, TK-684 reduces the protein expression of p-AKT and p-ERK.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C