TK-684

• Target:

  Apoptosis|||Phosphatase

• Related Pathways:

  Apoptosis|||Metabolism

• Bioactivity:

  TK-684 is a potent and selective allosteric inhibitor of SHP2, with IC50 values of 2.1 nM for SHP2WT and greater than 1000 nM for SHP2PTP. It inhibits cell proliferation and induces apoptosis (apoptosis) . Additionally, TK-684 reduces the protein expression of p-AKT and p-ERK.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C